Journal on Communications ›› 2017, Vol. 38 ›› Issue (12): 121-127.doi: 10.11959/j.issn.1000-436x.2017293

• Papers • Previous Articles     Next Articles

Research on full-field optical coherence tomography

Ning MU1,Wan-rong GAO1,Zhe-qiang WEI2   

  1. 1 School of Electronic Engineering and Optoelectronic Technology,Nanjing University of Science and Technology,Nanjing 210094,China
    2 Pathology Department,Wuxi No.3 People’s Hospital,Wuxi 214041,China
  • Revised:2017-11-28 Online:2017-12-01 Published:2018-01-19
  • Supported by:
    The National Natural Science Foundation of China(61275198);The National Natural Science Foundation of China(60978069)

Abstract:

Full-field optical coherence tomography(FFOCT)was used for imaging the interior part of an object.Firstly,the mathematical modeling and performance analysis of the FFOCT system mounted was provided.Secondly,images of several different human tissues were obtained by FFOCT system,including esophagus,uterus,etc.The images of different depths of the same tissue were shown and compared.It was the first time in China that FFOCT was used for generating depth images on human esophagus and uterus;high-resolution images had been obtained for different depths without cutting the tissue sample,in which intercellular substance and myofibril structure could be clearly identified.As the in-depth structure could be imaged without the process needed for frozen and paraffin sectioning methods,the technology could been highly valuable for early cancer diagnosis and pathological analysis in tumor research.

Key words: FFOCT, medical image, imaging performance, high resolution

CLC Number: 

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